Currently browsing: Items authored or edited by Laura Lopez-Cruz https://orcid.org/0000-0003-4735-6445

Lopez-Cruz, Laura; Phillips, Benjamin U; Hailwood, Jon M; Saksida, Lisa M; Heath, Christopher and Bussey, Timothy J (2024). Refining the study of decision-making in animals: differential effects of d-amphetamine and haloperidol in a novel touchscreen-automated Rearing-Effort Discounting (RED) task and the Fixed-Ratio Effort Discounting (FRED) task. Neuropsychopharmacology, 49 pp. 422–432.

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Cho, So Yeon; Kim, Eun Woo; Park, Soo Jin; Phillips, Benjamin U.; Jeong, Jihyeon; Kim, Hyunjeong; Heath, Christopher J.; Kim, Daehwan; Jang, Yurim; López-Cruz, Laura; Saksida, Lisa M.; Bussey, Timothy J.; Lee, Do Yup and Kim, Eosu (2024). Reconsidering repurposing: long-term metformin treatment impairs cognition in Alzheimer’s model mice. Translational Psychiatry, 14, article no. 34.

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Foerster, Sarah; Floriddia, Elisa M; van Bruggen, David; Kukanja, Petra; Herve, Bastien; Cheng, Shangli; Kim, Eosu; Phillips, Benjamin U; Heath, Christopher J; Tripathi, Richa B; Call, Cody; Bartels, Theresa; Ridley, Katherine; Neumann, Bjorn; Lopez-Cruz, Laura; Crawford, Abbe H; Lynch, Cian J; Serrano, Manuel; Saksida, Lisa; Rowitch, David H; Möbius, Wiebke; Nave, Klaus-Armin; Rasband, Matthew N; Bergles, Dwight E; Kessaris, Nicoletta; Richardson, Willam D; Bussey, Timothy J; Zhao, Chao; Castelo-Branco, Goncalo and Franklin, Robin J M (2024). Developmental origin of oligodendrocytes determines their function in the adult brain. Nature Neuroscience, 27(8) pp. 1545–1554.

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Dutcher, Ethan G; Lopez-Cruz, Laura; Pama EA, Claudia EA; Lynall, Mary-Ellen; Bevers, Iris CR; Jones, Joylon A; Khan, Shahid; Sawiak, Stephen J; Milton, Amy L; Clatworthy, Menna R; Robbins, Trevor W; Bullmore, Edward T and Dalley, Jeffrey W (2023). Early-life stress biases responding to negative feedback and increases amygdala volume and vulnerability to later-life stress. Translational Psychiatry, 13, article no. 81.

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Zühlsdorff, Katharina; Lopez-Cruz, Laura; Dutcher, Ethan G.; Jones, Jolyon A.; Pama, Claudia; Sawiak, Stephen; Khan, Shahid; Milton, Amy L.; Robbins, Trevor W.; Bullmore, Edward T. and Dalley, Jeffrey W. (2023). Sex-dependent effects of early life stress on reinforcement learning and limbic cortico-striatal functional connectivity. Neurobiology of Stress, 22, article no. 100507.

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Lopez-Cruz, Laura and Heath, Christopher J. (2022). Motivation – Behavioral Approaches and Translational Potential. In: Della Salla, Sergio ed. Encyclopedia of Behavioral Neuroscience, 2nd edition, Volume 2. Elsevier, pp. 60–69.

Lopez-Cruz, Laura; Bussey, Timothy J.; Saksida, Lisa M. and Heath, Christopher (2021). Using touchscreen-delivered cognitive assessments to address the principles of the 3Rs in behavioural sciences. Lab Animal, 50 pp. 174–184.

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Carratalá-Ros, Carla; Lopez-Cruz, Laura; Martínez-Verdú, Andrea; Olivares-García, Régulo; Salamone, John D. and Correa, Mercè (2021). Impact of Fluoxetine on Behavioral Invigoration of Appetitive and Aversively Motivated Responses: Interaction With Dopamine Depletion. Frontiers in Behavioral Neuroscience, 15, article no. 700182.

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Porru, Simona; López-Cruz, Laura; Carratalá‐Ros, Carla; Salamone, John D.; Acquas, Elio and Correa, Mercè (2021). Impact of Caffeine on Ethanol-Induced Stimulation and Sensitization: Changes in ERK and DARPP-32 Phosphorylation in Nucleus Accumbens. Alcoholism: Clinical and Experimental Research, 45(3) pp. 608–619.

Carratalá-Ros, Carla; Lopez-Cruz, Laura; SanMiguel, Noemí; Ibáñez-Marín, Patricia; Martínez-Verdú, Andrea; Salamone, John D. and Correa, Mercè (2020). Preference for Exercise vs. More Sedentary Reinforcers: Validation of an Animal Model of Tetrabenazine-Induced Anergia. Frontiers in Behavioral Neuroscience, 13

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Kim, Eosu; White, Matthew A.; Phillips, Benjamin U.; Lopez-Cruz, Laura; Kim, Hyunjeong; Heath, Christopher J.; Lee, Jong Eun; Saksida, Lisa M.; Sreedharan, Jemeen and Bussey, Timothy J. (2020). Coexistence of perseveration and apathy in the TDP-43^Q331K knock-in mouse model of ALS–FTD. Translational Psychiatry, 10(1), article no. 377.

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SanMiguel, N; Lopez-Cruz, L.; Müller, C.E.; Salamone, J.D. and Correa, M. (2019). Caffeine modulates voluntary alcohol intake in mice depending on the access conditions: Involvement of adenosine receptors and the role of individual differences. Pharmacology Biochemistry and Behavior, 186, article no. 172789.

Alsiö, Johan; Phillips, Benjamin U.; Sala-Bayo, Júlia; Nilsson, Simon R. O.; Calafat-Pla, Teresa C.; Rizwand, Arazo; Plumbridge, Jessica M.; Lopez-Cruz, Laura; Dalley, Jeffrey W.; Cardinal, Rudolf N.; Mar, Adam C. and Robbins, Trevor W. (2019). Dopamine D2-like receptor stimulation blocks negative feedback in visual and spatial reversal learning in the rat: behavioural and computational evidence. Psychopharmacology, 236(8) pp. 2307–2323.

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Luján, Miguel A.; Colomar, Laura; Tarragón, Ernesto; Lopez-Cruz, Laura; Pastor, Raúl and Font, Laura (2019). Drug-free and context-dependent locomotor hyperactivity in DBA/2 J mice previously treated with repeated cocaine: Relationship with behavioral sensitization and role of noradrenergic receptors. Pharmacology Biochemistry and Behavior, 176 pp. 101–110.

Phillips, Benjamin U.; Lopez-Cruz, Laura; Saksida, Lisa M. and Bussey, Timothy J. (2019). Translational tests involving non-reward: methodological considerations. Psychopharmacology, 236(1) pp. 449–461.

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Correa, Mercè; Lopez-Cruz, Laura; Porru, Simona and Salamone, John D. (2019). Chapter 56 - The Impact of Ethanol Plus Caffeine Exposure on Cognitive, Emotional, and Motivational Effects Related to Social Functioning. In: Preedy, Victor R. ed. Neuroscience of Alcohol. Academic Press, pp. 545–554.

Correa, Mercè; SanMiguel, Noemí; Lopez-Cruz, Laura; Carratalá-Ros, Carla; Olivares-García, Régulo and Salamone, John D. (2018). Caffeine Modulates Food Intake Depending on the Context That Gives Access to Food: Comparison With Dopamine Depletion. Frontiers in Psychiatry, 9, article no. 411.

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Lopez-Cruz, Laura; San Miguel, Noemí; Carratalá-Ros, Carla; Monferrer, Lidón; Salamone, John D. and Correa, Mercè (2018). Dopamine depletion shifts behavior from activity based reinforcers to more sedentary ones and adenosine receptor antagonism reverses that shift: Relation to ventral striatum DARPP32 phosphorylation patterns. Neuropharmacology, 138 pp. 349–359.

Lopez-Cruz, Laura; Salamone, John D. and Correa, Mercè (2018). Caffeine and Selective Adenosine Receptor Antagonists as New Therapeutic Tools for the Motivational Symptoms of Depression. Frontiers in Pharmacology, 9, article no. 526.

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SanMiguel, Noemí; Pardo, Marta; Carratalá-Ros, Carla; Lopez-Cruz, Laura; Salamone, John D. and Correa, Mercè (2018). Individual differences in the energizing effects of caffeine on effort-based decision-making tests in rats. Pharmacology Biochemistry and Behavior, 169 pp. 27–34.

Lopez-Cruz, Laura; Carbó-Gas, Maria; Pardo, Marta; Bayarri, Pilar; Valverde, Olga; Ledent, Catherine; Salamone, John D. and Correa, Mercè (2017). Adenosine A 2A receptor deletion affects social behaviors and anxiety in mice: Involvement of anterior cingulate cortex and amygdala. Behavioural Brain Research, 321 pp. 8–17.

Lopez-Cruz, Laura; San-Miguel, Noemí; Bayarri, Pilar; Baqi, Younis; Müller, Christa E.; Salamone, John D. and Correa, Mercé (2016). Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice: Involvement of Adenosine A2A and A1 Receptors. Frontiers in Behavioral Neuroscience, 10, article no. 206.

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Yohn, Samantha E.; Gogoj, Augustyna; Haque, Aileen; Lopez-Cruz, Laura; Haley, Allison; Huxley, Philip; Baskin, Patricia; Correa, Merce and Salamone, John D. (2016). Evaluation of the effort-related motivational effects of the novel dopamine uptake inhibitor PRX-14040. Pharmacology Biochemistry and Behavior, 148 pp. 84–91.

Salamone, John D.; Yohn, Samantha E.; Lopez-Cruz, Laura; San Miguel, Noemí and Correa, Mercè (2016). Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology. Brain, 139(5) pp. 1325–1347.

Salamone, John D.; Correa, Merce; Yohn, Samantha; Lopez Cruz, Laura; San Miguel, Noemi and Alatorre, Luisa (2016). The pharmacology of effort-related choice behavior: Dopamine, depression, and individual differences. Behavioural Processes, 127 pp. 3–17.

Salamone, John D.; Pardo, Marta; Yohn, Samantha E.; Lopez-Cruz, Laura; SanMiguel, Noemí and Correa, Mercè (2016). Mesolimbic Dopamine and the Regulation of Motivated Behavior. In: Simpson, Eleanor H. and Balsam, Peter eds. Behavioral Neuroscience of Motivation. Current Topics in Behavioral Neurosciences, 27. Springer International Publishing Switzerland, pp. 231–257.

Pardo, Marta; Lopez-Cruz, Laura; Miguel, Noemí San; Salamone, John D. and Correa, Mercè (2015). Selection of sucrose concentration depends on the effort required to obtain it: studies using tetrabenazine, D₁, D₂, and D₃ receptor antagonists. Psychopharmacology, 232(13) pp. 2377–2391.

Randall, P. A.; Lee, C. A.; Podurgiel, S. J.; Hart, E.; Yohn, S. E.; Jones, M.; Rowland, M.; Lopez-Cruz, Laura; Correa, M. and Salamone, J. D. (2015). Bupropion Increases Selection of High Effort Activity in Rats Tested on a Progressive Ratio/Chow Feeding Choice Procedure: Implications for Treatment of Effort-Related Motivational Symptoms. International Journal of Neuropsychopharmacology, 18(2), article no. pyu017.

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Yohn, Samantha E.; Lopez-Cruz, Laura; Hutson, Peter H.; Correa, Merce and Salamone, John D. (2015). Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat. Psychopharmacology, 233(6) pp. 949–960.

Correa, Mercè; Pardo, Marta; Bayarri, Pilar; Lopez-Cruz, Laura; San Miguel, Noemí; Valverde, Olga; Ledent, Catherine and Salamone, John D. (2015). Choosing voluntary exercise over sucrose consumption depends upon dopamine transmission: effects of haloperidol in wild type and adenosine A_2AKO mice. Psychopharmacology, 233(3) pp. 393–404.

Lopez-Cruz, Laura; Pardo, Marta; Salamone, John D. and Correa, Mercè (2014). Differences between the nonselective adenosine receptor antagonists caffeine and theophylline in motor and mood effects: Studies using medium to high doses in animal models. Behavioural Brain Research, 270 pp. 213–222.

Nunes, E. J.; Randall, P. A.; Hart, E. E.; Freeland, C.; Yohn, S. E.; Baqi, Y.; Muller, C. E.; Lopez-Cruz, L.; Correa, M. and Salamone, J. D. (2013). Effort-Related Motivational Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Animal Models of the Motivational Symptoms of Depression. Journal of Neuroscience, 33(49) pp. 19120–19130.

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Podurgiel, S.J.; Nunes, E.J.; Yohn, S.E.; Barber, J.; Thompson, A.; Milligan, M.; Lee, C.A.; López-Cruz, L.; Pardo, M.; Valverde, O.; Lendent, C.; Baqi, Y.; Müller, C.E.; Correa, M. and Salamone, J.D. (2013). The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: Implications for pharmacological models of parkinsonian tremor. Neuroscience, 250 pp. 507–519.

Lopez-Cruz, Laura; San, Miguel; Carbó-Gas, Maria; Bayarri, Pilar; Pardo, Marta; Ros, Xavier; Valverde, Olga; Ledent, Catherine; Salamone, John and Correa, Mercè (2013). E.21 - CAFFEINE INDUCES ANXIETY AND IMPAIRS SOCIAL INTERACTION IN MICE: THE ROLE OF ADENOSINE RECEPTORS AND IMPACT ON ETHANOL. In: Behavioural Pharmacology, Wolters Kluwer Health | Lippincott Williams & Wilkins, 24 e47.

Correa, Mercè; Lopez-Cruz, Laura; Bayarri, Pilar; Pardo, Marta; San Miguel, Noemí; Ros, Xavier and Salamone, John (2013). S.2.4 - RUNNERS VS. COUCH POTATOES: DOPAMINE DEPLETION REDUCES SELECTION OF PHYSICAL EFFORT IN ANIMALS WITH LOW BUT NOT HIGH EXPERIENCE OF EXERCISE. In: Behavioural Pharmacology, Wolters Kluwer Health | Lippincott Williams & Wilkins, 24 e3-e4.

Pardo, M.; Lopez-Cruz, L.; Valverde, O.; Ledent, C.; Baqi, Y.; Müller, C.E.; Salamone, J.D. and Correa, M. (2013). Effect of subtype-selective adenosine receptor antagonists on basal or haloperidol-regulated striatal function: Studies of exploratory locomotion and c-Fos immunoreactivity in outbred and A_2AR KO mice. Behavioural Brain Research, 247 pp. 217–226.

Lopez-Cruz, Laura; Salamone, John D. and Correa, Mercè (2013). The Impact of Caffeine on the Behavioral Effects of Ethanol Related to Abuse and Addiction: A Review of Animal Studies. Journal of Caffeine Research, 3(1) pp. 9–21.

Pardo, Marta; Betz, Adrienne J.; San Miguel, Noemí; Lopez-Cruz, Laura; Salamone, John D. and Correa, Mercè (2013). Acetate as an active metabolite of ethanol: studies of locomotion, loss of righting reflex, and anxiety in rodents. Frontiers in Behavioral Neuroscience, 7, article no. 81.

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Segovia, Kristen N.; Vontell, Regina; Lopez-Cruz, Laura; Salamone, John D. and Correa, Mercè (2013). c-Fos immunoreactivity in prefrontal, basal ganglia and limbic areas of the rat brain after central and peripheral administration of ethanol and its metabolite acetaldehyde. Frontiers in Behavioral Neuroscience, 7, article no. 48.

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Salamone, John D.; Correa, Merce; Randall, Patrick A.; Nunes, Eric J.; Pardo, Marta and Lopez-Cruz, Laura (2013). The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation. In: Masino, Susan and Boison, Detlev eds. Adenosine: A Key Link between Metabolism and Brain Activity. Springer-Verlag New York, pp. 493–512.

Santerre, Jessica L.; Nunes, Eric J.; Kovner, Rotem; Leser, Chelsea E.; Randall, Patrick A.; Collins-Praino, Lyndsey E.; Lopez-Cruz, Laura; Correa, Merce; Baqi, Younis; Müller, Christa E. and Salamone, John D. (2012). The novel adenosine A_2A antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions. Pharmacology Biochemistry and Behavior, 102(4) pp. 477–487.

Pardo, M.; Lopez-Cruz, L.; Valverde, O.; Ledent, C.; Baqi, Y.; Müller, C.E.; Salamone, J.D. and Correa, M. (2012). Adenosine A_2A receptor antagonism and genetic deletion attenuate the effects of dopamine D₂ antagonism on effort-based decision making in mice. Neuropharmacology, 62(5-6) pp. 2068–2077.

Randall, Patrick A.; Pardo, Marta; Nunes, Eric J.; Lopez-Cruz, Laura; Vemuri, V. Kiran; Makriyannis, Alex; Baqi, Younis; Müller, Christa E.; Correa, Mercè and Salamone, John D. (2012). Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences. PLoS ONE, 7(10), article no. e47934.

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Lopez-Cruz, Laura; Pardo, Marta; Salamone, John D and Correa, Merce (2011). Comparison between high doses of caffeine and theophylline on motor and axiogenic effects in CD1 mice: studies of acute and chronic administration. In: Behavioural Pharmacology, Behavioral Pharmachology, 22 e1-e73.