Currently browsing: Items authored or edited by Francesco Crea https://orcid.org/0000-0002-4903-2973

Salani, Francesca; Eccleston, Mark; Palmieri, Lola-Jade; Pernot, Simon; Cousin, Sophie; Masi, Gianluca; Crea, Francesco and Italiano, Antoine (2024). Circulating H3K27me3 modified nucleosomes as a biomarker to monitor anti EZH2-based treatment in advanced solid tumour patients: Translational analyses from CAIRE trial. Cancer Research, 84(6_Suppl.), article no. 5128.

Smith, Kayleigh; Beach, Dan; Silva, Roger; Balazs, Gyorffy; Salani, Francesca and Crea, Francesco (2024). Comprehensive analysis of differentially expressed miRNAs in hepatocellular carcinoma: Prognostic, predictive significance and pathway insights. PLOS ONE, 19(4), article no. e0296198.

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Holt, Daniel; Contu, Laura; Wood, Alice; Chadwick, Hannah; Alborelli, Ilaria; Insilla, Andrea Cacciato; Crea, Francesco and Hawkes, Cheryl A. (2024). Both Maternal High-Fat and Post-Weaning High-Carbohydrate Diets Increase Rates of Spontaneous Hepatocellular Carcinoma in Aged-Mouse Offspring. Nutrients, 16(16), article no. 2805.

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Wang, Yuzhuo; Scurll, Joshua; Rascón, Itzel Astiazarán; Cui, Cassandra; Ni, Yuchao; Shi, Ace Mingchen; Gangadharannambiar, Priyadarsini; Wang, Yu; Akamatsu, Shusuke; Beltran, Himisha; Cox, Michael; Crea, Francesco; Daugaard, Mads; Dong, Xuesen; Haffner, Michael; He, Hansen; Jachetti, Elena; Kyprianou, Natasha; Li, Benyi; Ong, Christopher E; Rickman, David S; Sen, Triparna; Zhu, Helen He; Zoubeidi, Amina and Gleave, Martin E (2024). The third symposium on treatment-induced neuroendocrine prostate cancer: insights and future directions. Epigenomics (Early access).

Silvestri, Roberto; Nicolì, Vanessa; Gangadharannambiar, Priyadarsini; Crea, Francesco and Bootman, Martin D. (2023). Calcium signalling pathways in prostate cancer initiation and progression. Nature reviews. Urology, 20 pp. 524–543.

Qin, Yi; Ashrafizadeh, Milad; Mongiardini, Vera; Grimaldi, Benedetto; Crea, Francesco; Rietdorf, Katja; Győrffy, Balázs; Klionsky, Daniel J; Ren, Jun; Zhang, Wei and Zhang, Xianbin (2023). Autophagy and cancer drug resistance in dialogue: Pre-clinical and clinical evidence. Cancer letters, 570, article no. 216307.

Salani, F.; Guerri, V.; Cesario, S.; Sammuri, P.; Genovesi, V.; Pratesi, F.; Massa, V.; Catanese, S.; Vivaldi, C.; Fornaro, L.; Crea, F.; Migliorini, P.; Galimberti, S. and Masi, G. (2023). P-54 Circulating immune cells as a tool to predict benefit from atezolizumab/bevacizumab in advanced hepatocellular carcinoma (aHCC). Annals of Oncology, 34 S32.

Montuori, Eleonora; Hyde, Caroline; Crea, Francesco; Golding, Jon and Lauritano, Chiara (2023). Marine Natural Products with Activities against Prostate Cancer: Recent Discoveries. International Journal of Molecular Sciences, 24(2), article no. 1435.

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Grint, Isobel; Crea, Francesco and Vasiliadou, Rafaela (2022). The Combination of Electrochemistry and Microfluidic Technology in Drug Metabolism Studies. ChemistryOpen, 11(12), article no. e202200100.

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Salani, Francesca; Latarani, Maryam; Casadei-Gardini, Andrea; Gangadharannambiar, Priyadarsini; Fornaro, Lorenzo; Vivaldi, Caterina; Pecora, Irene; Massa, Valentina; Marisi, Giorgia; Canale, Matteo; Ulivi, Paola; Scartozzi, Mario; Eccleston, Mark; Masi, Gianluca and Crea, Francesco (2022). Predictive significance of circulating histones in hepatocellular carcinoma patients treated with sorafenib. Epigenomics, 14(9) pp. 507–517.

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Lavik, Andrew R.; McColl, Karen S.; Lemos, Fernanda O.; Kerkhofs, Martijn; Zhong, Fei; Harr, Michael; Schlatzer, Daniela; Hamada, Kozo; Mikoshiba, Katsuhiko; Crea, Francesco; Bultynck, Geert; Bootman, Martin D.; Parys, Jan B. and Distelhorst, Clark W. (2022). A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca²⁺ signalling through IP₃ receptors. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1869(4), article no. 119206.

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Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hushmandi, Kiavash; Hashemi, Farid; Zabolian, Amirhossein; Canadas, Israel; Zarrabi, Ali; Nabavi, Noushin; Aref, Amir Reza; Crea, Francesco; Wang, Yuzhuo; Ashrafizadeh, Milad and Kumar, Alan Prem (2022). The long and short non-coding RNAs modulating EZH2 signaling in cancer. Journal of Hematology & Oncology, 15(1)

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Ashrafizadeh, Milad; Paskeh, Mahshid Deldar Abad; Mirzaei, Sepideh; Gholami, Mohammad Hossein; Zarrabi, Ali; Hashemi, Farid; Hushmandi, Kiavash; Hashemi, Mehrdad; Nabavi, Noushin; Crea, Francesco; Ren, Jun; Klionsky, Daniel J.; Kumar, Alan Prem and Wang, Yuzhuo (2022). Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response. Journal of Experimental & Clinical Cancer Research, 41(1), article no. 105.

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Wang, Yong; Wang, Yu; Ci, Xinpei; Choi, Stephen Y C; Crea, Francesco; Lin, Dong and Wang, Yuzhuo (2021). Molecular events in neuroendocrine prostate cancer development. Nature Reviews Urology, 18(10) pp. 581–596.

Ashrafizaveh, Saeed; Ashrafizadeh, Milad; Zarrabi, Ali; Husmandi, Kiavash; Zabolian, Amirhossein; Shahinozzaman, Md; Aref, Amir Reza; Hamblin, Michael R.; Nabavi, Noushin; Crea, Francesco; Wang, Yuzhuo and Ahn, Kwang Seok (2021). Long non-coding RNAs in the doxorubicin resistance of cancer cells. Cancer Letters, 508 pp. 104–114.

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Frias Anaya, Eduardo; Gromnicova, Radka; Kraev, Igor; Rogachevsky, Vadim; Male, David; Crea, Francesco; Hawkes, Cheryl and Romero, Ignacio A. (2021). Age-related ultrastructural neurovascular changes in the female mouse cortex and hippocampus. Neurobiology of Aging, 101 pp. 273–284.

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Mather, Rebecca L.; Parolia, Abhijit; Carson, Sandra E.; Venalainen, Erik; Roig-Carles, David; Jaber, Mustapha; Chu, Shih‐Chun; Alborelli, Ilaria; Wu, Rebecca; Lin, Dong; Nabavi, Noushin; Jachetti, Elena; Colombo, Mario P.; Xue, Hui; Pucci, Perla; Ci, Xinpei; Hawkes, Cheryl; Li, Yinglei; Pandha, Hardev; Ulitsky, Igor; Marconett, Crystal; Quagliata, Luca; Jiang, Wei; Romero, Ignacio A; Wang, Yuzhuo and Crea, Francesco (2021). The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms. Molecular Oncology, 15(7) pp. 1921–1941.

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Roig-Carles, David; Jackson, Holly; Loveson, Katie F.; Mackay, Alan; Mather, Rebecca; Waters, Ella; Manzo, Massimiliano; Alborelli, Ilaria; Golding, Jon; Jones, Chris; Fillmore, Helen L. and Crea, Francesco (2021). The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation. International Journal of Molecular Sciences, 22(17), article no. 9165.

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Latarani, Maryam; Pucci, Perla; Roig-Carles, David; Eccleston, Mark; Xue, Hui; Hawkes, Cheryl; Rigas, Sushila; Wang, Yuzhuo and Crea, Francesco (2020). EZH2 as a therapeutic target for aggressive prostate cancer. In: Crick Cancer Research Symposium, iPoster, 5-6 Oct 2020, The Francis Crick Institute and Virtual.

Pucci, Perla; Crea, Francesco; Alborelli, Ilaria; Quagliata, Luca; Bootman, Martin; Rigas, Sushilaben; Romero, Ignacio and Wang, Yuzhuo (2020). Long non-coding RNAs are key players in Prostate cancer tumorigenesis and drug resistance. In: 27th Annual PCF Scientific Retreat Virtual Poster Session, 20-23 Oct 2020, Virtual, Morressier.

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Kang, Ning; Eccleston, Mark; Clermont, Pier-Luc; Latarani, Maryam; Male, David Kingsley; Wang, Yuzhuo and Crea, Francesco (2020). EZH2 inhibition: a promising strategy to prevent cancer immune editing. Epigenomics, 12(16)

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Pucci, Perla; Venalainen, Erik; Alborelli, Ilaria; Quagliata, Luca; Hawkes, Cheryl; Mather, Rebecca; Romero, Ignacio A; Rigas, Sushila; Wang, Yuzhuo and Crea, Francesco (2020). LncRNA HORAS5 promotes taxane resistance in castration-resistant prostate cancer via a BCL2A1-dependent mechanism. Epigenomics, 12(13) pp. 1123–1138.

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Mather, Rebecca; Andrews, Henry; Pandha, Hardev; Jachetti, Elena; Micallef, Jake; Wang, Yuzhuo and Crea, Francesco (2020). The Open University’s first one day symposium on treatment-emergent neuroendocrine prostate cancer. In: Future Oncology, Future Medicine.

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Ayaz, Sameer and Crea, Francesco (2020). Targeting SARS-CoV-2 using polycomb inhibitors as antiviral agents. Epigenomics, 12(10)

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Pucci, P.; Venalainen, E.; Alborelli, I.; Quagliata, L.; Mather, R.; Rigas, S.; Romero, I.; Wang, Y. and Crea, F. (2019). HORAS5 promotes cabazitaxel resistance in castration resistant prostate cancer via a BCL2A1-dependent survival mechanism. Annals of Oncology, 30(5) v798.

Crea, Francesco (2019). Neuroendocrine prostate cancer: long noncoding RNAs to treat an incurable cancer – an interview with Dr Francesco Crea. Epigenomics, 11(13) pp. 1461–1462.

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Silvestri, Roberto; Pucci, Perla; Venalainen, Erik; Matheou, Chrysanthi; Mather, Rebecca; Chandler, Stephen; Aceto, Romina; Rigas, Sushila; Wang, Yuzhuo; Rietdorf, Katja; Bootman, Martin and Crea, Francesco (2019). T-type calcium channels drive the proliferation of androgen-receptor negative prostate cancer cells. The Prostate, 79(13) pp. 1580–1586.

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Parolia, Abhijit; Venalainen, Erik; Xue, Hui; Mather, Rebecca; Lin, Dong; Wu, Rebecca; Pucci, Perla; Rogalski, Jason; Evans, Joseph; Feng, Felix; Collins, Colin; Wang, Yuzhuo and Crea, Francesco (2019). The long non-coding RNA HORAS5 mediates castration-resistant prostate cancer survival by activating the androgen receptor transcriptional program. Molecular Oncology, 13(5) pp. 1121–1136.

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Clermont, Pier-Luc; Ci, Xinpei; Pandha, Hardev; Wang, Yuzhuo and Crea, Francesco (2019). Treatment-emergent neuroendocrine prostate cancer: molecularly driven clinical guidelines. International Journal of Endocrine Oncology, 6(2), article no. IJE20.

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Chandler, Stephen; Gangadharannambiar, Priyadarsini; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushila (2019). Discovery of candidate hub genes in breast cancer. In: New Developments in Breast Cancer Research - From the Lab to the Clinic, 2019 BACR Special Conference, 9-11 Oct 2019, The Sage, Newcastle Gateshead, UK.

Chandler, Stephen; Gangadharannambiar, Priyadarsini; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushila (2019). Discovery of candidate long non-coding RNAs as biomarkers and treatment targets for prostate cancer. In: NEPC 2019. Treatment-emergent neuroendocrine prostate cancer: clinical relevance and molecular pathogenesis., 25 Jun 2019, The Open University, Milton Keynes, UK.

White, Jasmine Cassar; Pucci, Perla and Crea, Francesco (2019). The role of histone lysine demethylases in cancer cells' resistance to tyrosine kinase inhibitors. Cancer Drug Resistance, 2(2) pp. 326–334.

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Mather, Rebecca L.; Wang, Yuzhuo and Crea, Francesco (2018). Is HOTAIR really involved in neuroendocrine prostate cancer differentiation? Epigenomics, 10(10) pp. 1259–1261.

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Pucci, Perla; Rescigno, Pasquale; Sumanasuriya, Semini; de Bono, Johann and Crea, Francesco (2018). Hypoxia and Noncoding RNAs in Taxane Resistance. Trends in Pharmacological Sciences, 39(8) pp. 695–709.

Ci, Xinpei; Hao, Jun; Dong, Xin; Choi, Stephen Y.C.; Xue, Hui; Wu, Rebecca; Qu, Sifeng; Gout, Peter W.; Zhang, Fang; Haegert, Anne M.; Fazil, Ladan; Crea, Francesco; Ong, Christopher J.; Zoubedi, Amina; He, Housheng H.; Gleave, Martin E.; Collins, Colin C.; Lin, Dong and Wang, Yuzhuo (2018). Heterochromatin protein 1α mediates development and aggressiveness of neuroendocrine prostate cancer. Cancer Research, 78(10) pp. 2691–2704.

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Juan-Larrea, Naiara; Mather, Rebecca; Romero, Ignacio A.; Sibson, Nicola R. and Crea, Francesco (2018). The role of long non-coding RNAs in breast cancer dissemination to the brain. In: CRUK brain tumour conference, 1-3 May 2018, London.

Chandler, Stephen; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushila (2018). Identification of candidate genes that may function in ER- breast cancer. In: BACR Conference: Response and Resistance in Cancer Therapy, 10-12 Sep 2018, University of Kent, Canterbury.

Paolicchi, Elisa; Fornaro, Lorenzo; Landi, Stefano; Rigas, Sushilaben and Crea, Francesco (2017). EZH2 Single Nucleotide Variants (SNVs): Diagnostic and Prognostic Role in 10 Solid Tumor Types. Epigenomes, 1(3), article no. 18.

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Chandler, Stephen; Crea, Francesco; Hirst, Mark; Cox, Angela and Rigas, Sushilaben (2017). Identification of putative functional genes in breast and other cancers with potentially shared aetiology. In: The Human Genome in Healthcare, 23-24 Nov 2017, The Royal Society, London, UK.

Clermont, Pier-Luc; Fornaro, Lorenzo and Crea, Francesco (2017). Elevated expression of a pharmacologic Polycomb signature predicts poor prognosis in gastric and breast cancer. Epigenomics, 9(10) pp. 1329–1335.

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Fornaro, Lorenzo; Vivaldi, Caterina; Lin, Dong; Xue, Hui; Falcone, Alfredo; Wang, Yuzhuo; Crea, Francesco and Bootman, Martin D. (2017). Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation. PLoS ONE, 12(8), article no. e0182818.

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Mather, Rebecca L.; Hirst, Mark and Crea, Francesco (2017). Are there any HOTTIPs for defining coding potential of lncRNAs, or just a lot of HOTAIR? Epigenomics, 9(8) pp. 1045–1047.

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Nabavi, Noushin; Saidy, Nur Ridzwan Nur; Venalainen, Erik; Haegert, Anne; Parolia, Abhijit; Xue, Hui; Wang, Yuwei; Wu, Rebecca; Dong, Xin; Collins, Colin; Crea, Francesco and Wang, Yuzhuo (2017). miR-100-5p inhibition induces apoptosis in dormant prostate cancer cells and prevents the emergence of castration-resistant prostate cancer. Scientific reports, 7(1), article no. 4079.

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Mather, Rebecca L.; Venalainen, Erik; Pucci, Perla; Lin, Dong; Xue, Hui; Wang, Yuzhuo and Crea, Francesco (2017). The long non-coding RNA NEAR1 promotes neuroendocrine prostate cancer cell proliferation and survival. In: 3rd International Cancer Symposium, Cancer Research Center of Lyon (CRCL), 25-27 Sep 2017, Lyon, France.

Pucci, Perla; Venalainen, Erik; Mather, Rebecca; Xue, Hui; Rigas, Sushila; Romero, Ignacio A; Wang, Yuzho and Crea, Francesco (2017). Identification of a long non-coding RNA that mediates response to therapy in castration-resistant prostate cancer. In: 3rd International Cancer Symposium, 25-27 Sep 2017, Lyon, France.

Paolicchi, E.; Vivaldi, C.; De Gregorio, V.; Crea, F.; Fornaro, L.; Masi, G.; Loupakis, F.; Graziano, F.; Ronzoni, M.; Ricci, V.; Falcone, A. and Danesi, R. (2016). Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients. Oncology, 91(5) pp. 283–288.

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Matheou, Chrysanthi; Chandler, Stephen; Crea, Francesco; Faria, Nuno; Powell, Jonathan; McDonald, Fraser; Rietdorf, Katja and Bootman, Martin D. (2016). Mibefradil; a T-type calcium channel blocker as a potential anti-cancer agent. In: 14th International Meeting of the European Calcium Society, 25-29 Sep 2016, Valladolid, Spain.

Crea, Francesco; Venalainen, Erik; Ci, Xinpei; Cheng, Hongwei; Pikor, Larissa; Parolia, Abhijit; Xue, Hui; Nur Saidy, Nur Ridzwan; Lin, Dong; Lam, Wan; Collins, Colin and Wang, Yuzhuo (2016). The role of epigenetics and long noncoding RNA MIAT in neuroendocrine prostate cancer. Epigenomics, 8(5) pp. 721–731.

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Crea, Francesco; Quagliata, Luca; Michael, Agnieszka; Liu, Hui Hsuan; Frumento, Paolo; Azad, Arun A.; Xue, Hui; Pikor, Larissa; Wathaiki, Akira; Morant, Rudolf; Castori-Eppenberger, Serenella; Wang, Yuwei; Parolia, Abhijit; Lennox, Kim A.; Lam, Wan L.; Gleave, Martin; Chi, Kim N.; Pandha, Hardev; Wang, Yuzhuo and Helgason, Cheryl D. (2016). Integrated analysis of the prostate cancer small-nucleolar transcriptome reveals SNORA55 as a driver of prostate cancer progression. Molecular Oncology, 10(5) pp. 693–703.

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Clermont, Pier-Luc; Crea, Francesco; Chiang, Yan Ting; Lin, Dong; Zhang, Amy; Wang, James Z. L.; Parolia, Abhijit; Wu, Rebecca; Xue, Hui; Wang, Yuwei; Ding, Jiarui; Thu, Kelsie L.; Lam, Wan L.; Shah, Sohrab P.; Collins, Colin C.; Wang, Yuzhuo and Helgason, Cheryl D. (2016). Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer. Clinical Epigenetics, 8, article no. 16.

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Fornaro, Lorenzo; Faviana, Pinuccia; De Gregorio, Veronica; Vivaldi, Caterina; Paolicchi, Elisa; Masi, Gianluca; Loupakis, Fotios; Sensi, Elisa; Lupi, Cristiana; Fontanini, Garbriella; Wang, Yuzhuo; Danesi, Romano; Falcone, Alfredo and Crea, Francesco (2015). Molecular and pathological characterization of the EZH2 rs3757441 single nucleotide polymorphism in colorectal cancer. BMC Cancer, 15, article no. 874.

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Crea, Francesco; Di Paolo, Antonello; Liu, Hui Hsuan; Polillo, Marialuisa; Clermont, Pier-Luc; Guerrini, Francesca; Ciabatti, Elena; Ricci, Federica; Baratè, Claudia; Fontanelli, Giulia; Barsotti, Sara; Morganti, Riccardo; Danesi, Romano; Wang, Yuzhuo; Petrini, Mario; Galimberti, Sara and Helgason, Cheryl D. (2015). Polycomb genes are associated with response to imatinib in chronic myeloid leukemia. Epigenomics, 7(5) pp. 757–765.

Clermont, Pier-Luc; Lin, Dong; Crea, Francesco; Wu, Rebecca; Xue, Hui; Wang, Yuwei; Thu, Kelsie L; Lam, Wan L; Collins, Colin C; Wang, Yuzhuo and Helgason, Cheryl D (2015). Polycomb-mediated silencing in neuroendocrine prostate cancer. Clinical Epigenetics, 7(40)

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Crea, Francesco; Nur Saidy, Nur Ridzwan; Collins, Colin C. and Wang, Yuzhuo (2015). The epigenetic/noncoding origin of tumor dormancy. Trends in molecular medicine, 21(4) pp. 206–11.

Lin, Dong; Dong, Xin; Wang, Kendric; Wyatt, Alexander W.; Crea, Francesco; Xue, Hui; Wang, Yuwei; Wu, Rebecca; Bell, Robert H.; Haegert, Anne; Brahmbhatt, Sonal; Hurtado-Coll, Antonio; Gout, Peter W.; Fazli, Ladan; Gleave, Martin E.; Collins, Colin C. and Wang, Yuzhuo (2015). Identification of DEK as a potential therapeutic target for neuroendocrine prostate cancer. Oncotarget, 6(3) pp. 1806–1820.

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Clermont, P-L; Sun, L; Crea, F; Thu, K L; Zhang, A; Parolia, A; Lam, W L and Helgason, C D (2014). Genotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role. British Journal of Cancer, 111(8) pp. 1663–1672.

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Crea, Francesco; Clermont, Pier-Luc; Mai, Antonello and Helgason, Cheryl D. (2014). Histone modifications, stem cells and prostate cancer. Current Pharmaceutical Design, 20(11) pp. 1687–1697.

Crea, Francesco; Clermont, Pier Luc; Parolia, Abhijit; Wang, Yuzhuo and Helgason, Cheryl D. (2014). The non-coding transcriptome as a dynamic regulator of cancer metastasis. Cancer Metastasis Reviews, 33(1) pp. 1–16.

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Crea, Francesco; Watahiki, Akira; Quagliata, Luca; Xue, Hui; Pikor, Larissa; Parolia, Abhijit; Wang, Yuwei; Lin, Dong; Lam, Wan L.; Farrar, William L.; Isogai, Takao; Morant, Rudolf; Castori-Eppenberger, Serenella; Chi, Kim N.; Wang, Yuzhuo and Helgason, Cheryl D. (2014). Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer. Oncotarget, 5(3) pp. 764–774.

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Crea, Francesco and Fornaro, Lorenzo (2014). Genome-epigenome interactions: the Polycomb paradox. Epigenomics, 6(1) pp. 5–7.

Crea, F.; Sun, L.; Pikor, L.; Frumento, P.; Lam, W. L. and Helgason, C. D. (2013). Mutational analysis of Polycomb genes in solid tumours identifies PHC3 amplification as a possible cancer-driving genetic alteration. British Journal of Cancer, 109(6) pp. 1699–1702.

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Paolicchi, Elisa; Crea, Francesco; Farrar, William L.; Green, Jeffrey E. and Danesi, Romano (2013). Histone lysine demethylases in breast cancer. Critical Reviews in Oncology/Hematology, 86(2) pp. 97–103.

Watahiki, Akira; Macfarlane, Robyn J.; Gleave, Martin E.; Crea, Francesco; Wang, Yuzhuo; Helgason, Cheryl D. and Chi, Kim N. (2013). Plasma miRNAs as biomarkers to identify patients with castration-resistant metastatic prostate cancer. International Journal of Molecular Sciences, 14(4) pp. 7757–7770.

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Duhagon, M. A.; Crea, F.; Danesi, R. and Farrar, W. L. (2013). Embryonic stem cell pathways and chemotherapy response: an unexplored route. Annals of Oncology, 24(2) pp. 558–559.

Crea, Francesco; Fornaro, Lorenzo; Bocci, Guido; Sun, Lei; Farrar, William L.; Falcone, Alfredo and Danesi, Romano (2012). EZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis. Cancer and Metastasis reviews, 31(3) pp. 753–761.

Crea, Francesco; Sun, Lei; Mai, Antonello; Chiang, Yan Ting; Farrar, William L.; Danesi, Romano and Helgason, Cheryl D. (2012). The emerging role of histone lysine demethylases in prostate cancer. Molecular Cancer, 11, article no. 52.

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Avan, Amir; Crea, Francesco; Paolicchi, Elisa; Funel, Niccola; Galvani, Elena; Marquez, Victor E; Honeywell, Richard J; Danesi, Romano; Peters, Godefridus J and Giovannetti, Elisa (2012). Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells. Molecular Cancer Therapeutics, 11(8) pp. 1735–1746.

Crea, Francesco; Paolicchi, Elisa; Marquez, Victor E. and Danesi, Romano (2012). Polycomb genes and cancer: time for clinical application? Critical Reviews in Oncology/Hematology, 83(2) pp. 184–193.

Crea, F.; Fornaro, L.; Paolicchi, E.; Masi, G.; Frumento, P.; Loupakis, F.; Salvatore, L.; Cremolini, C.; Schirripa, M.; Graziano, F.; Ronzoni, M.; Ricci, V.; Farrar, W. L.; Falcone, A. and Danesi, R. (2012). An EZH2 polymorphism is associated with clinical outcome in metastatic colorectal cancer patients. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO, 23(5) pp. 1207–13.

Crea, Francesco (2012). Histone code, human growth and cancer. Oncotarget, 3(1) pp. 1–2.

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Crea, Francesco; Nobili, Stefania; Paolicchi, Elisa; Perrone, Gabriele; Napoli, Cristina; Landini, Ida; Danesi, Romano and Mini, Enrico (2011). Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies. Drug Resistance Updates, 14(6) pp. 280–296.

Crea, Francesco; Fornaro, Lorenzo; Masi, Gianluca; Falcone, Alfredo; Danesi, Romano and Farrar, William (2011). Faithful markers of circulating cancer stem cells: is CD133 sufficient for validation in clinics? Journal of Clinical Oncology, 29(25) pp. 3487–3488.

Donzella, Valentina and Crea, Francesco (2011). Optical biosensors to analyze novel biomarkers in oncology. Journal of Biophotonics, 4(6) pp. 442–452.

Crea, Francesco; Hurt, Elaine M.; Mathews, Lesley A.; Cabarcas, Stephanie M.; Sun, Lei; Marquez, Victor E.; Danesi, Romano and Farrar, William L. (2011). Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer. Molecular Cancer, 10, article no. 40.

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Crea, Francesco; Duhagon Serrat, Maria A.; Hurt, Elaine M.; Thomas, Suneetha B.; Danesi, Romano and Farrar, William L. (2011). BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer. International Journal of Cancer, 128(8) pp. 1946–1954.

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Crea, Francesco (2011). EZH2 and cancer stem cells: fact or fiction? Epigenomics, 3(2) pp. 127–128.

Crea, Francesco; Hurt, Elaine M. and Farrar, William L. (2010). Clinical significance of Polycomb gene expression in brain tumors. Molecular Cancer, 9, article no. 265.

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Pastina, Ilaria; Giovannetti, Elisa; Chioni, Aldo; Sissung, Tristan M.; Crea, Francesco; Orlandini, Cinzia; Price, Douglas K.; Cianci, Claudia; Figg, William D.; Ricci, Sergio and Danesi, Romano (2010). Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients. BMC Cancer, 10, article no. 511.

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Ricciardi, S.; Mey, V.; Nannizzi, S.; Pasqualetti, G.; Crea, F.; Del Tacca, M. and Danesi, R. (2010). Synergistic cytotoxicity and molecular interaction on drug targets of sorafenib and gemcitabine in human pancreas cancer cells. Chemotherapy, 56(4) pp. 303–312.

Crea, Francesco; Mathews, Lesley A.; Farrar, William L. and Hurt, Elaine M. (2009). Targeting prostate cancer stem cells. Anti-cancer agents in medicinal chemistry, 9(10) pp. 1105–1113.

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